Genetic Analyses of Contributions of Viral Interleukin-6 Interactions and Signaling to Human Herpesvirus 8 Productive Replication

Genetic Analyses of Contributions of Viral Interleukin-6 Interactions and Signaling to Human Herpesvirus 8 Productive Replication

Human herpesvirus 8 (HHV-8) virus interleukin-6 (vIL-6) is a cytokine that is secreted and most poorly translated into the endoplasmic reticulum (ER). Has been involved, along with HHV-8 viral proteins pro-inflammatory and / or other angiogenic, in HHV-8-related Kaposi’s sarcoma, primary effusion lymphoma (PEL), and multicentric Castleman’s disease (MCD), in addition to an MCD -related disorders involving elevation of systemic pro-inflammatory cytokines, including human vIL-6 and IL-6 (HIL-6). In this disease, lytic (productive) replication, in addition to viral latency, is believed to play an important role.

Pro-replication activity of vIL-6 has been identified experimentally in PEL and endothelial cells, but the relative contribution of different vIL-6 interaction has not been established. productive interaction of vIL-6 to IL-6 signal transducer, gp130, can occur in the ER, but vIL-6 also interact in the ER with a receptor called vitamin K epoxide non-signal reductase subunit complex 1 variant-2 (VKORC1v2), calnexin, and VKORC1v2- and related calnexin protein UDP-glucose: glycoprotein glucosyltransferase 1 (UGGT1) and glucosidase II (GlucII). Here, we report a systematic characterization of the interaction-modified vIL-6 variants and recombinant virus expressing the lytic phenotype selected variants.

Our data identifies the importance of vIL-6 and the activity of ER-localized it through gp130 to replicate productively in iSLK (induced epithelial) cells, the lack of involvement of detectable vIL-6 interaction with VKORC1v2, GlucII or UGGT1, and the insufficiency and lack of effect of direct contributions from extracellular signals by vIL-6 or Hil-6. These findings, obtained through genetic-based approach, complementing and extending the previous analysis of vIL-6 activity.IMPORTANCE Human herpesvirus 8 (HHV-8) -encoded viral interleukin-6 (vIL-6) was the first viral IL-6 homologues to be identified.

Experimental and clinical evidence indicates that vIL-6 is important for the onset and / or progression of the pathology associated with HHV-8 B-cells, and endothelial, including AIDS-related Kaposi’s sarcoma and multicentric Castleman’s disease. Protein is unusual in poor secretion of the cells and the intracellular activity; interact, directly or indirectly, with a number of outer protein IL-6 signal transducer, gp130, and may mediate this interaction activities through the endoplasmic reticulum.

Here, we characterize in connection with protein interactions and signal transducing activity of vIL-6 variant panels and take advantage of HHV-8 virus mutants expressing variant selected in the phenotypic analysis. Our findings establish the importance of vIL-6 in HHV-8 replication productive and individual contributions interaction of vIL-6 protein to HHV-8 lytic biology. This work furthers the understanding of the biological importance of vIL-6 and a unique intracellular interactions.

 Genetic Analyses of Contributions of Viral Interleukin-6 Interactions and Signaling to Human Herpesvirus 8 Productive Replication
Genetic Analyses of Contributions of Viral Interleukin-6 Interactions and Signaling to Human Herpesvirus 8 Productive Replication

Impact of interleukin IL-6 rs-1474347 and IL-10-rs 1800896 susceptibility genetic polymorphisms in Egypt HCV-infected patients to hepatocellular carcinoma

The hepatitis C virus (HCV) is considered a major cause of cirrhosis and hepatocellular carcinoma (HCC). We aimed to determine the relationship of IL-6 and IL-10 single nucleotide polymorphisms with the development of chronic hepatitis C (CHC) infection to cirrhosis and liver cancer.

Human Interleukin-3 (IL-3) Antibody (Biotin Conjugate)

30128-05121 150 ug
EUR 442.8

Interleukin-1 Receptor 3 (IL-1R3) Antibody

20-abx141734
  • EUR 444.00
  • EUR 727.20
  • EUR 360.00
  • 100 ul
  • 200 ul
  • 50 ul

IL-3, Interleukin-3, rat

RC252-14 2ug
EUR 121.6

IL-3, Interleukin-3, human

RC212-14 2ug
EUR 125.26

IL-3, Interleukin-3, monkey

RC222-14 2ug
EUR 125.26

IL-3, Interleukin-3, canine

RC242-14 2ug
EUR 125.26

Human Interleukin-3 (IL-3) AssayLite Antibody (RPE Conjugate)

30128-05151 150 ug
EUR 513.6

Human Interleukin-3 (IL-3) AssayLite Antibody (APC Conjugate)

30128-05161 150 ug
EUR 513.6

Human Interleukin-3 (IL-3) AssayLite Antibody (FITC Conjugate)

30128-05141 150 ug
EUR 513.6

Human Interleukin-3 (IL-3) AssayLite Antibody (PerCP Conjugate)

30128-05171 150 ug
EUR 565.2

IL-3, Interleukin-3, murine (mouse)

RC232-14 2ug
EUR 125.26

Interleukin-29 (IL-29) Antibody

abx234264-100ug 100 ug
EUR 661.2

Interleukin-29 (IL-29) Antibody

abx234265-100ug 100 ug
EUR 661.2

Interleukin-28A (IL-28A) Antibody

abx234261-100ug 100 ug
EUR 661.2

Interleukin-28A (IL-28A) Antibody

abx234262-100ug 100 ug
EUR 661.2

Interleukin 4 (IL-4) Antibody

abx234279-100ug 100 ug
EUR 661.2

Interleukin 6 (IL-6) Antibody

abx234282-100ug 100 ug
EUR 661.2

Interleukin 6 (IL-6) Antibody

abx234283-100ug 100 ug
EUR 661.2

Interleukin 7 (IL-7) Antibody

abx234285-100ug 100 ug
EUR 610.8

Interleukin-3 (IL3) Antibody

abx411132-05mg 0.5 mg
EUR 794.4

Interleukin-3 (IL3) Antibody

abx411440-02mg 0.2 mg
EUR 678

Interleukin-3 (IL3) Antibody

abx411687-01mg 0.1 mg
EUR 844.8

Interleukin 32 (IL-32) Antibody

abx216212-100ug 100 ug
EUR 526.8

Interleukin 18 (IL-18) Antibody

20-abx225240
  • EUR 444.00
  • EUR 727.20
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 50 ul

Interleukin 21 (IL-21) Antibody

20-abx225244
  • EUR 444.00
  • EUR 727.20
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 50 ul

Interleukin 27 (IL-27) Antibody

20-abx225246
  • EUR 444.00
  • EUR 727.20
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 50 ul

Interleukin 10 (IL-10) Antibody

abx234211-100ug 100 ug
EUR 661.2

Interleukin 10 (IL-10) Antibody

abx234212-100ug 100 ug
EUR 661.2

Interleukin 16 (IL-16) Antibody

abx234223-100ug 100 ug
EUR 661.2

Interleukin 17 (IL-17) Antibody

abx234224-100ug 100 ug
EUR 610.8

Interleukin 17 (IL-17) Antibody

abx234225-100ug 100 ug
EUR 577.2

Interleukin 19 (IL-19) Antibody

abx234233-100ug 100 ug
EUR 661.2

Interleukin 19 (IL-19) Antibody

abx234234-100ug 100 ug
EUR 661.2

Interleukin 19 (IL-19) Antibody

abx234235-100ug 100 ug
EUR 661.2

Interleukin 24 (IL-24) Antibody

abx234257-100ug 100 ug
EUR 610.8

Interleukin 24 (IL-24) Antibody

abx234258-100ug 100 ug
EUR 661.2

Interleukin 27 (IL-27) Antibody

abx234259-100ug 100 ug
EUR 661.2

Interleukin 27 (IL-27) Antibody

abx234260-100ug 100 ug
EUR 661.2

Interleukin 25 (IL-25) Antibody

abx430547-200ul 200 ul
EUR 460.8

Interleukin 25 (IL-25) Antibody

abx430548-200ul 200 ul
EUR 460.8

Interleukin 10 (IL-10) Antibody

abx432852-200ul 200 ul
EUR 343.2

Interleukin 15 (IL-15) Antibody

abx432855-200ul 200 ul
EUR 460.8

Rat IL-3(Interleukin-3) ELISA Kit

ER0040 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 9.375pg/ml

Interleukin 3 (IL3) Antibody

abx216209-100ug 100 ug
EUR 526.8

Interleukin 3 (IL3) Antibody

20-abx211999
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Interleukin 3 (IL3) Antibody

abx234268-100ug 100 ug
EUR 661.2

Interleukin 3 (IL3) Antibody

20-abx113252
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Interleukin 3 (IL3) Antibody

20-abx173151
  • EUR 944.40
  • EUR 493.20
  • 1 mg
  • 200 ug

Interleukin 3 (IL3) Antibody

20-abx173152
  • EUR 1011.60
  • EUR 526.80
  • 1 mg
  • 200 ug

Interleukin 3 (IL3) Antibody

20-abx173153
  • EUR 1045.20
  • EUR 543.60
  • 1 mg
  • 200 ug

Interleukin 3 (IL3) Antibody

20-abx320427
  • EUR 360.00
  • EUR 292.80
  • 100 ul
  • 50 ul

Interleukin 3 (IL3) Antibody

abx037051-100ug 100 ug
EUR 469.2

Interleukin 3 (IL3) Antibody

20-abx006305
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Interleukin 3 (IL3) Antibody

20-abx109941
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 3 (IL3) Antibody

20-abx177161
  • EUR 1412.40
  • EUR 693.60
  • 1 mg
  • 200 ug

Interleukin 3 (IL3) Antibody

20-abx177162
  • EUR 526.80
  • EUR 159.60
  • EUR 1479.60
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 3 (IL3) Antibody

20-abx177163
  • EUR 1579.20
  • EUR 760.80
  • 1 mg
  • 200 ug

Interleukin 3 (IL3) Antibody

20-abx121630
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Interleukin 3 (IL3) Antibody

20-abx137020
  • EUR 427.20
  • EUR 627.60
  • 0.5 mg
  • 1 mg

Interleukin 3 (IL3) Antibody

20-abx128907
  • EUR 477.60
  • EUR 159.60
  • EUR 1328.40
  • EUR 644.40
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 3 (IL3) Antibody

20-abx131301
  • EUR 543.60
  • EUR 159.60
  • EUR 1545.60
  • EUR 744.00
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 3 (IL3) Antibody

20-abx131302
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 3 (IL3) Antibody

20-abx131303
  • EUR 493.20
  • EUR 159.60
  • EUR 1362.00
  • EUR 661.20
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 3 (IL3) Antibody

20-abx131304
  • EUR 493.20
  • EUR 159.60
  • EUR 1362.00
  • EUR 661.20
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

IL-3 beta, Interleukin-3-beta, rat

RC252-14B 5ug
EUR 121.6

Rat Interleukin 3 (IL-3) CLIA Kit

abx195894-96tests 96 tests
EUR 990

Rat Interleukin 3,IL-3 ELISA KIT

CN-01500R1 96T
EUR 520.8

Rat Interleukin 3,IL-3 ELISA KIT

CN-01500R2 48T
EUR 340.8

Rat Interleukin 3, IL-3 ELISA KIT

CSB-E07436r-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Rat Interleukin 3, IL-3 in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat Interleukin 3, IL-3 ELISA KIT

1-CSB-E07436r
  • EUR 723.60
  • EUR 5096.40
  • EUR 2712.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Rat Interleukin 3, IL-3 in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rat Interleukin 3(IL-3)ELISA Kit

GA-E0140RT-48T 48T
EUR 380.4

Rat Interleukin 3(IL-3)ELISA Kit

GA-E0140RT-96T 96T
EUR 595.2

Rat Interleukin 3(IL-3)ELISA Kit

QY-E11513 96T
EUR 433.2

Rat Interleukin 3,IL-3 ELISA KIT

YLA0010RA-48T 48T
EUR 465

Rat Interleukin 3,IL-3 ELISA KIT

YLA0010RA-96T 96T
EUR 600

Human Interleukin 3 (IL-3) CLIA Kit

abx195892-96tests 96 tests
EUR 990

Mouse Interleukin 3 (IL-3) CLIA Kit

abx195893-96tests 96 tests
EUR 990

Human Interleukin 3,IL-3 ELISA KIT

201-12-0094 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Mouse Interleukin 3,IL-3 ELISA KIT

CN-02449M1 96T
EUR 536.4

Mouse Interleukin 3,IL-3 ELISA KIT

CN-02449M2 48T
EUR 355.2

Human Interleukin 3,IL-3 ELISA KIT

CN-03207H1 96T
EUR 520.8

Human Interleukin 3,IL-3 ELISA KIT

CN-03207H2 48T
EUR 340.8

Human Interleukin 3, IL-3 ELISA KIT

CSB-E04631h-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Human Interleukin 3, IL-3 in samples from serum, plasma. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Interleukin 3, IL-3 ELISA KIT

1-CSB-E04631h
  • EUR 600.00
  • EUR 4082.40
  • EUR 2184.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Interleukin 3, IL-3 in samples from serum, plasma. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Interleukin 3, IL-3 ELISA KIT

CSB-E04632m-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Mouse Interleukin 3, IL-3 in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse Interleukin 3, IL-3 ELISA KIT

1-CSB-E04632m
  • EUR 600.00
  • EUR 4082.40
  • EUR 2184.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Mouse Interleukin 3, IL-3 in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse IL-3(Interleukin 3) ELISA Kit

EM0116 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 9.375pg/ml

Human IL-3(Interleukin 3) ELISA Kit

EH0196 96T
EUR 571.5
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml

Mouse Interleukin 3(IL-3)ELISA Kit      

GA-E0074MS-48T 48T
EUR 403.2

Mouse Interleukin 3(IL-3)ELISA Kit      

GA-E0074MS-96T 96T
EUR 640.8

Human Interleukin 3(IL-3)ELISA Kit

GA-E0133HM-48T 48T
EUR 346.8

Human Interleukin 3(IL-3)ELISA Kit

GA-E0133HM-96T 96T
EUR 559.2

Human Interleukin 3(IL-3)ELISA Kit

QY-E04273 96T
EUR 433.2

Mouse Interleukin 3(IL-3)ELISA Kit

QY-E20857 96T
EUR 433.2

Human Interleukin 3,IL-3 ELISA KIT

YLA1520HU-48T 48T
EUR 435

Human Interleukin 3,IL-3 ELISA KIT

YLA1520HU-96T 96T
EUR 562.5

Mouse Interleukin 3,IL-3 ELISA KIT      

YLA0099MO-48T 48T
EUR 465

Mouse Interleukin 3,IL-3 ELISA KIT      

YLA0099MO-96T 96T
EUR 600

Rat Interleukin-33 (IL-33) Antibody

32099-05111 150 ug
EUR 313.2

Rabbit Interleukin 3,IL-3 ELISA Kit

CN-00724R1 96T
EUR 542.4

Rabbit Interleukin 3,IL-3 ELISA Kit

CN-00724R2 48T
EUR 362.4

Rabbit Interleukin 3,IL-3 ELISA Kit

GA-E0115RB-48T 48T
EUR 391.2

Rabbit Interleukin 3,IL-3 ELISA Kit

GA-E0115RB-96T 96T
EUR 628.8

Rabbit Interleukin 3,IL-3 ELISA Kit

GA-E0116RB-48T 48T
EUR 391.2

Rabbit Interleukin 3,IL-3 ELISA Kit

GA-E0116RB-96T 96T
EUR 628.8

Rabbit Interleukin 3,IL-3 ELISA Kit

QY-E30183 96T
EUR 448.8

Canine Interleukin 3(IL-3)ELISA Kit

YLA0058CA-48T 48T
EUR 502.5

Canine Interleukin 3(IL-3)ELISA Kit

YLA0058CA-96T 96T
EUR 618.75

Chicken Interleukin 3,IL-3 ELISA Kit

CN-00791C1 96T
EUR 520.8

Chicken Interleukin 3,IL-3 ELISA Kit

CN-00791C2 48T
EUR 340.8

PoFAine interleukin 3,IL-3 ELISA Kit

CN-01254P1 96T
EUR 542.4

PoFAine interleukin 3,IL-3 ELISA Kit

CN-01254P2 48T
EUR 362.4

Chicken Interleukin 3, IL-3 ELISA Kit

CSB-E09877Ch-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Chicken Interleukin 3, IL-3 in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Chicken Interleukin 3, IL-3 ELISA Kit

1-CSB-E09877Ch
  • EUR 752.40
  • EUR 5336.40
  • EUR 2836.80
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Chicken Interleukin 3, IL-3 in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Chicken IL-3(Interleukin 3) ELISA Kit

ECH0043 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Chicken;Sensitivity: 9.375pg/ml

Chicken Interleukin 3,IL-3 ELISA Kit

QY-E80039 96T
EUR 511.2

Porcine interleukin 3 (IL-3) ELISA Kit

QY-E40139 96T
EUR 480

Porcine interleukin 3,IL-3 ELISA Kit

YLA0023PO-48T 48T
EUR 502.5

Porcine interleukin 3,IL-3 ELISA Kit

YLA0023PO-96T 96T
EUR 618.75

Recombinant Human Interleukin-3 (rHu IL-3)

AK9836-0010 10ug
EUR 570

Recombinant Human Interleukin-3 (rHu IL-3)

AK9836-0100 100ug
EUR 2160

Human Interleukin-8 (IL-8) Antibody

13102-05011 150 ug
EUR 248.4

Mouse Interleukin-2 (IL-2) Antibody

13115-05011 150 ug
EUR 260.4

Human Interleukin-6 (IL-6) Antibody

13122-05011 150 ug
EUR 260.4

Human Interleukin-2 (IL-2) Antibody

30175-05111 150 ug
EUR 313.2

Mouse Interleukin-6 (IL-6) Antibody

32031-05111 150 ug
EUR 313.2

Mouse Interleukin-6 (IL-6) Antibody

33020-05111 150 ug
EUR 313.2

Human Interleukin-9 (IL-9) Antibody

32578-05111 150 ug
EUR 313.2

Human Interleukin-4 (IL-4) Antibody

32184-05111 150 ug
EUR 313.2

Human Interleukin-10 (IL-10) Antibody

13109-05011 150 ug
EUR 260.4

Human Interleukin-33 (IL-33) Antibody

30029-05111 150 ug
EUR 313.2

Human Interleukin-15 (IL-15) Antibody

30145-05111 150 ug
EUR 313.2

Human Interleukin-16 (IL-16) Antibody

32243-05111 150 ug
EUR 313.2

Human Interleukin-25 (IL-25) Antibody

32566-05111 150 ug
EUR 313.2

Human Interleukin-18 (IL-18) Antibody

32199-05111 150 ug
EUR 313.2

Mouse Interleukin-15 (IL-15) Antibody

32200-05111 150 ug
EUR 313.2

Mouse Interleukin-18 (IL-18) Antibody

30119-05111 150 ug
EUR 313.2

Human Interleukin-29 (IL-29) Antibody

35625-05111 150 ug
EUR 313.2

Human Interleukin-32 (IL-32) Antibody

35729-05111 150 ug
EUR 313.2

Human Interleukin-34 (IL-34) Antibody

35731-05111 150 ug
EUR 313.2

Interleukin-36 Alpha (IL-36A) Antibody

20-abx225247
  • EUR 444.00
  • EUR 727.20
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 50 ul

IL-3 Interleukin-3 Rat Recombinant Protein

PROTP04823 Regular: 20ug
EUR 380.4
Description: Interleukin-3 Rat Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 144 amino acids and having a molecular mass of 16.3kDa. ;The IL-3 is purified by proprietary chromatographic techniques.

Human Interleukin-17A (IL-17A) Antibody

32118-05111 150 ug
EUR 313.2

Human Interleukin-17F (IL-17F) Antibody

32233-05111 150 ug
EUR 313.2

Human Interleukin-3 (IL-3) AssayLite Antibody (FITC, RPE, APC, PerCP Conjugate)

30128-05181 1 x 75 ug, 3 x 30 ug
EUR 702

IL-3 Interleukin-3 Mouse Recombinant Protein

PROTP01586 Regular: 10ug
EUR 380.4
Description: Interleukin-3 mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 135 amino acids and having a molecular mass of 15100 Dalton. ;The IL-3 is purified by proprietary chromatographic techniques.

IL-3 Interleukin-3 Human Recombinant Protein

PROTP08700-1 Regular: 10ug
EUR 380.4
Description: Interleukin-3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 133 amino acids and having a molecular mass of 15000 Dalton. The IL-3 is purified by proprietary chromatographic techniques.

Interleukin-23 Receptor (IL-23R) Antibody

20-abx225245
  • EUR 444.00
  • EUR 727.20
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 50 ul

Interleukin 3 (IL3) Antibody (HRP)

20-abx108429
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

CLIA kit for Rat IL-3 (Interleukin 3)

E-CL-R0390 1 plate of 96 wells
EUR 700.8
Description: A sandwich CLIA kit for quantitative measurement of Rat IL-3 (Interleukin 3) in samples from Serum, Plasma, Cell supernatant

Guinea pig Interleukin-3 IL-3 ELISA KIT

CN-00265G1 96T
EUR 548.4

Guinea pig Interleukin-3 IL-3 ELISA KIT

CN-00265G2 48T
EUR 367.2

Interleukin 3 (IL3) Antibody (FITC)

20-abx107008
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

ELISA kit for Rat IL-3 (Interleukin 3)

E-EL-R0556 1 plate of 96 wells
EUR 640.8
Description: A sandwich ELISA kit for quantitative measurement of Rat IL-3 (Interleukin 3) in samples from Serum, Plasma, Cell supernatant

CLIA kit for Human IL-3 (Interleukin 3)

E-CL-H0099 1 plate of 96 wells
EUR 700.8
Description: A sandwich CLIA kit for quantitative measurement of Human IL-3 (Interleukin 3) in samples from Serum, Plasma, Cell supernatant

CLIA kit for Mouse IL-3 (Interleukin 3)

E-CL-M0454 1 plate of 96 wells
EUR 700.8
Description: A sandwich CLIA kit for quantitative measurement of Mouse IL-3 (Interleukin 3) in samples from Serum, Plasma, Cell supernatant

Interleukin 6 Receptor (IL-6R) Antibody

abx149042-100ug 100 ug
EUR 526.8

ELISA kit for Mouse IL-3 (Interleukin 3)

E-EL-M0721 1 plate of 96 wells
EUR 640.8
Description: A sandwich ELISA kit for quantitative measurement of Mouse IL-3 (Interleukin 3) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human IL-3 (Interleukin 3)

E-EL-H0100 1 plate of 96 wells
EUR 640.8
Description: A sandwich ELISA kit for quantitative measurement of Human IL-3 (Interleukin 3) in samples from Serum, Plasma, Cell supernatant

Interleukin 3 (IL3) Antibody (Biotin)

20-abx105590
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Recombinant Human Interleukin-3/IL-3 (N-6His)

CF63-10ug 10ug
EUR 187.2
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Human Interleukin-3/IL-3 (N-6His)

CF63-1mg 1mg
EUR 2739.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Human Interleukin-3/IL-3 (N-6His)

CF63-500ug 500ug
EUR 1935.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Human Interleukin-3/IL-3 (N-6His)

CF63-50ug 50ug
EUR 442.8
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Mouse Interleukin-3/IL-3 (C-6His)

CP39-10ug 10ug
EUR 242.4
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Mouse Interleukin-3/IL-3 (C-6His)

CP39-1mg 1mg
EUR 2983.2
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Mouse Interleukin-3/IL-3 (C-6His)

CP39-500ug 500ug
EUR 2106
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Mouse Interleukin-3/IL-3 (C-6His)

CP39-50ug 50ug
EUR 595.2
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human Interleukin-3/IL-3 (C-6His)

CX90-10ug 10ug
EUR 187.2
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

Recombinant Human Interleukin-3/IL-3 (C-6His)

CX90-1mg 1mg
EUR 2739.6
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

Recombinant Human Interleukin-3/IL-3 (C-6His)

CX90-500ug 500ug
EUR 1935.6
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

Recombinant Human Interleukin-3/IL-3 (C-6His)

CX90-50ug 50ug
EUR 442.8
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

IL-3 Interleukin-3 Human Recombinant Protein, HEK

PROTP08700 Regular: 10ug
EUR 380.4
Description: Interleukin-3 Human Recombinant produced in HEK cells is a glycosylated monomer, having a molecular weight range of 17-45kDa due to glycosylation.;The IL-3 is purified by proprietary chromatographic techniques.

IL-3 Interleukin-3 Human Recombinant Protein, Sf9

PROTP08700-2 Regular: 10ug
EUR 380.4
Description: Interleukin-3 Human Recombinant produced in insect cells is a single, glycosylated polypeptide chain containing 133 amino acids and having a molecular mass of 15000 Dalton. ;The IL-3 CSF is fused to a C-terminal His-tag (6x His) and purified by proprietary chromatographic techniques.

Interleukin-1 Receptor 9 (IL-1R9) Antibody

20-abx216200
  • EUR 510.00
  • EUR 410.40
  • 100 ug
  • 50 ug

IL-3 ELISA Kit| Rat Interleukin-3 ELISA Kit

EF017037 96 Tests
EUR 826.8

For comparison purposes, the four groups were registered; groups of chronic hepatitis C (CHC, n = 22), related to HCV-group liver cirrhosis (HCV-LC, n = 22), related to HCV-group of HCC (HCV-HCC, n = 54), and a control group that looked healthy (control , n = 48). HCC diagnosis and staging are in concordance to the Barcelona Clinic Liver Cancer (BCLC) staging system. IL-6 rs-1474347 and IL-10-rs 1800896 genotype performed by allele (VIC- and FAM-labeled) discrimination method using test-on-demand real-time TaqMan PCR test.

Djoumana

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