Interleukin 4 Genetics for Cell Culture

Fit Products – Pathway Genomics

Enhancing immune responses by a novel multi-epitope ROP8 DNA vaccine plus interleukin-12 plasmid as a genetic adjuvant against acute Toxoplasma gondii infection in BALB/c mice

Enhancing immune responses by a novel multi-epitope ROP8 DNA vaccine plus interleukin-12 plasmid as a genetic adjuvant against acute Toxoplasma gondii infection in BALB/c mice

Background: Toxoplasmosis is a widespread zoonotic infection, caused by the obligate intracellular protozoan. The infection is often asymptomatic in immunocompetent individuals, although in people with impaired immune systems can cause severe complications and progressive. constant efforts scientists have made valuable discoveries in the development of Toxoplasma gondii (T. gondii) vaccine candidate. However, an effective vaccine has not been developed yet. In the current study, we tested the co-delivery of multi-epitope vaccine pcROP8 new plasmid DNA encoding IL-12 (pcIL-12) to assess immune responses in BALB / c mice against acute T. gondii infection.


Methods: BALB / c mice were immunized on days 0, 21, and 42. The immune response of the vaccinated and control groups were evaluated using measurements of cytokines and antibodies, lymphocyte proliferation test, and survival time.


Results: The findings show that immunization with a multi-epitope pcROP8 significantly increase the level of anti-T. gondii antibodies, cellular immune responses TH1-type, lymphocyte proliferation, and survival time is long, compared with the control group (P <0.05). Furthermore, the use of pcIL-12 as an adjuvant genetic causes enhancement of the immune response mentioned above BALB / c mice (P <0.05).


Conclusion: The co-administration of pcIL-12 with a multi-epitope vaccine pcROP8, can be managed to increase the level of protection. Thus, this immunization regimen may be an effective vaccine strategies against T. gondii acute infection.

 Enhancing immune responses by a novel multi-epitope ROP8 DNA vaccine plus interleukin-12 plasmid as a genetic adjuvant against acute Toxoplasma gondii infection in BALB/c mice
Enhancing immune responses by a novel multi-epitope ROP8 DNA vaccine plus interleukin-12 plasmid as a genetic adjuvant against acute Toxoplasma gondii infection in BALB/c mice

Genetic Variants FOXP3 Do Not Impact Supply and Cervical Interleukin-10 Levels in Human Papillomavirus Infection in Women

Regulatory T cells (Treg) heredity plays a central role in the control of inflammation and autoimmunity. Interleukin-10 (IL-10) has been described as a pleiotropic cytokine that is mainly released by CD4 + CD25 + FOXP3 + Treg and has strong immunosuppressive activity. Forkhead box P3 (FOXP3) expression of the transcription factor is very important for Treg function as a suppressor cells and FOXP3 gene single nucleotide variants (SNVs) has been shown to influence the pathogenesis of the virus.

This study was conducted to evaluate the plasmatic and cervical level of IL-10 in patients papillomavirus infected and uninfected humans and investigate whether intron -1 FOXP3 SNVs rs3761548 and rs2232365 may alter IL-10 secretion. SNVs characterization genotyped by polymerase chain reaction (PCR) products based on a specific sequence of enzymatic cleavage using restriction fragment length polymorphism method (RFLP). IL-10 levels determined by quantitative enzyme-linked immunosorbent assay (ELISA). In conclusion, the data show that there is no relationship between FOXP3 and cervical SNVs and circulating IL-10 level. These findings provide a reason that the IL-10 gene activation is independent of the transcription factor FOXP3 activity on Treg cells.


Introduction: We aimed to determine the genetic polymorphism and serum levels of interleukin 18 in Fars ethnic groups.Material and methods: 226 Fars ethnic groups participate. ATP III criteria were used to assess components of MS. SNP of the IL-18 gene was determined by ARMS-PCR.Results: The GG, GC and CC genotypes of -137 is 50%, 40% and 10%. CC, CA and AA genotypes of -607 is 45%, 37%, and 18% ..

Recombinant Human Relaxin-2 Protein

PROTP04090-2 25ug
EUR 317
Description: Relaxin-2 is a peptide hormone structurally related to insulin, which is expressed in the placenta, decidua, prostate, and in the ovary during pregnancy. Of the three known relaxin genes, Relaxin-2 is the only relaxin known to circulate in the blood. Relaxin-2 binds specifically to the LGR7 and LGR8 receptors, previously identified as an “orphan” G protein coupled receptors. Signaling by Relaxin-2 through its target receptors enhances the growth of pubic ligaments and ripening of the cervix during birth. Recombinant Relaxin-2 is a nonglycosylated 6.0 kDa disulfide linked heterodimeric protein consisting of a 24 amino acid A-chain and a 29 amino acid B-chain.

Recombinant Human PAI-2 Protein

PROTP05120-2 10ug
EUR 317
Description: PAI-2 is an inhibitory serpin expressed mainly in keratinocytes, activated monocytes, and placental trophoblasts. It exists predominantly as a 47 kDa nonglycosylated intracellular protein which can be induced to be secreted as 60 kDa glycoprotein. The glycosylated and unglycosylated forms of PAI-2 are equally effective as inhibitors of urokinase-type plasminogen activator (uPA), the only established physiological target of this serpin. PAI-2 has a unique ability to form dormant polymers spontaneously and reversibly under physiological conditions. The physiological relevance of this property, which is neither a consequence of any mutation in the PAI-2 gene nor associated with any known disorder, is still unclear. However, it appears that the formation of intracellular dormant polymers may be important for the controlled release of the inhibitor from PAI-2 producing cells. Plasma levels of PAI-2 are usually low or undetectable, except during pregnancy and in some forms of monocytic leukemia. Secretion of PAI-2 from the placenta normally occurs during the third trimester of pregnancy and accounts for the dramatic increase in PAI-2 levels (up to 250 ng/ml), which are maintained at these levels until postpartum, and then rapidly decline. In addition to its vital role in protecting the placenta from degradation by uPA and/or uPA-activated proteases, PAI-2 has been shown to be essential for the prevention of metastatic spread of neck, lung and breast cancers. The beneficial effect of PAI-2 seen in these studies is presumed to stem from its ability to inhibit uPA-dependent cell dissemination. PAI-2 has also been reported to inhibit keratinocyte proliferation, and to participate in the innate immune response during viral infection. Recombinant human PAI-2 is a 415-residue nonglycosylated protein.

Recombinant Human MMP-2 Protein

PROTP08253-2 10ug
EUR 317
Description: Matrix metalloproteinases (MMPs) are a family of endoproteases that require zinc and calcium for expressing catalytic activity. These enzymes play a central role in the maintenance and remodeling of the extracellular matrix. Elevated expression of their activity, caused either by up-regulation of their expression or down-regulation of their cognate inhibitors, has been implicated in various degenerative disorders, including arthritis, cardiovascular disease, skeletal growth-plate disorders, and cancer metastasis. MMP-2 is a secreted collagenase with specificity toward Type IV, V, VII, and X collagens. Recombinant human MMP-2 is a 62.0 kDa protein containing the entire catalytic N-terminal domain and the C-terminal domain (552 amino acids).

Recombinant Human BD-2 Protein

PROTO15263-2 20ug
EUR 317
Description: Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds. To date, six human β-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. β-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence and in some cases, a propeptide sequence. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant human BD-2 is a 4.3 kDa protein containing 41 amino acid residues.

BMP-2 Bone Morphogenetic Protein-2 Human Recombinant Protein, Monomer

PROTP12643-2 Regular: 20ug
EUR 317
Description: Bone Morphogenetic Protein-2 Human Recombinant produced in E.Coli is a monomeric, non-glycosylated, Polypeptide chain containing 115 amino acids (283-396) and having a molecular mass of 13009 Dalton. ;The BMP-2 is purified by proprietary chromatographic techniques.

ErbB2 ErbB-2 Human Recombinant Protein

PROTP04626-2 Regular: 20ug
EUR 317
Description: ErbB-2 Human Recombinant is a 43.4 kDa protein containing 397 amino acid residues of the human Herstatin, and an extra Methionine at N-Terminal (underlined), produced in E.coli.

IL15 Human, Interleukin-15 Human Recombinant Protein, HEK

PROTP40933-2 Regular: 10ug
EUR 317
Description: Interleukin-15 Human Recombinant produced in HEK cells is a glycosylated monomer, having a molecular weight of 12.8kDa due to glycosylation.;The IL15 is purified by proprietary chromatographic techniques.

IL17B Human, Interleukin-17B Human Recombinant Protein, Sf9

PROTQ9UHF5-2 Regular: 5ug
EUR 317
Description: IL17B Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 169 amino acids (21-180a.a.) and having a molecular mass of 19.2kDa (Molecular size on SDS-PAGE will appear at approximately 18-28kDa). IL17B is expressed with a 6 amino acid His-tag at C-Terminus and purified by proprietary chromatographic techniques.

IL-7 Interleukin-7 Human Recombinant Protein

PROTP13232-2 Regular: 10ug
EUR 317
Description: Interleukin-7 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 152 amino acids and having a molecular mass of 17.4 kDa. ;The IL-7 is purified by proprietary chromatographic techniques.

IL-10 Interleukin-10 Human Recombinant Protein

PROTP22301-2 Regular: 10ug
EUR 317
Description: Interleukin-10 Human Recombinant produced in E.coli is a single non-glycosylated polypeptide chains containing 161 amino acids each and having a molecular mass of 18.6kDa.;The IL-10 is purified by proprietary chromatographic techniques.

Recombinant Murine IL-2 Protein

PROTP04351-2 20ug
EUR 317
Description: IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant murine IL-2 is a 17.2 kDa protein, containing 149 amino acid residues.

Mouse FGF-2 Recombinant Protein

R00121-2 5ug/vial
EUR 259
Description: FGF basic (FGF2) is a multipotential fibroblast growth factor that stimulates and supports proliferation, migration and differentiation. Mouse FGF basic (FGF-2) Recombinant Protein is purified FGF basic (FGF-2) produced in yeast.

Chicken IL-2 Recombinant Protein

R00387-2 5ug/vial
EUR 259
Description: Interleukin-2 (IL-2) is a cytokine produced by T-helper cells in response to antigenic or mitogenic stimulation. It is required for T-cell proliferation and other activities crucial to the regulation of the immune response. Chicken IL-2 Recombinant Protein is purified interleukin-2 produced in yeast.

Recombinant Human TGF-Beta 2 (insect derived) Protein

PROTP61812-2 10ug
EUR 317
Description: The three mammalian isoforms of TGF-β, TGF-β1, β2, β3, signal through the same receptor and elicit similar biological responses. They are multifunctional cytokines that regulate cell proliferation, growth, differentiation and motility as well as synthesis and deposition of the extracellular matrix. They are involved in various physiological processes including embryogenesis, tissue remodeling and wound healing. They are secreted predominantly as latent complexes which are stored at the cell surface and in the extracellular matrix. The release of biologically active TGF-β isoform from a latent complex involves proteolytic processing of the complex and /or induction of conformational changes by proteins such as thrombospondin-1. TGF-β2 has been shown to exert suppressive effects on IL-2 dependent T-cell growth, and may also have an autocrine function in enhancing tumor growth by suppressing immuno-surveillance of tumor development. Recombinant human TGF-β2 is a 25.0 kDa protein composed of two identical 112 amino acid polypeptide chains linked by a single disulfide bond.
* Manufactured using (BTI-Tn-5B1-4) cells under license from the Boyce Thompson Institute for Plant Research, Inc.

Nori® Human Angiopoietin-2 (ANG-2) ELISA Kit (2 plates)

GR106245-2 2 x 96-well
EUR 832

IL1A Human, Interleukin-1 alpha Human Recombinant Protein, HEK

PROTP01583-2 Regular: 10ug
EUR 317
Description: Interleukin-1 alpha Human Recombinant produced in HEK cells is a glycosylated monomer, having a molecular weight of 18kDa due to glycosylation.;The IL1A is purified by proprietary chromatographic techniques.

IL-4 Interleukin-4 Human Recombinant Protein, CHO

PROTP05112-2 Regular: 10ug
EUR 317
Description: Interleukin-4 Human Recombinant produced in CHO is a single, non-glycosylated polypeptide chain containing 129 amino acids and having a molecular mass of 14 kDa, the glycosilation of IL-4 migrates as 18 kDa on SDS-PAGE.;The IL-4 is purified by proprietary chromatographic techniques.

IL-6 Interleukin-6 Recombinant Protein Human, CHO

PROTP05231-2 Regular: 20ug
EUR 317
Description: Interleukin-6 Human Recombinant produced in CHO is a 21-23kDa single, glycosylated polypeptide chain containing 183 amino acids.

IL-3 Interleukin-3 Human Recombinant Protein, Sf9

PROTP08700-2 Regular: 10ug
EUR 317
Description: Interleukin-3 Human Recombinant produced in insect cells is a single, glycosylated polypeptide chain containing 133 amino acids and having a molecular mass of 15000 Dalton. ;The IL-3 CSF is fused to a C-terminal His-tag (6x His) and purified by proprietary chromatographic techniques.

IL-9 Interleukin-9 Human Recombinant Protein, Sf9

PROTP15248-2 Regular: 10ug
EUR 317
Description: IL-9 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain (19-144 a.a.) including an 18 aa signal peptide (1-18 aa) and fused to a 6 aa His Tag at C-terminus containing a total of 150 amino acids and having a molecular mass of 14.5kDa.;IL9 shows multiple bands between 18-28kDa on SDS-PAGE, reducing conditions and purified by proprietary chromatographic techniques.

Nori Human TIM-2 ELISA Kit-2 Plates

GR111039-2 2 x 96-well
EUR 832

Nori® Human b-defensin 2 (BD-2) ELISA Kit- 2 Plates

GR111099-2 2 x 96-well
EUR 832

Nori® Human MMP-2/TIMP-2 Complex ELISA Kit (2 plates)

GR106372-2 2 x 96-well
EUR 832

PLGF2 Human, Placenta Growth Factor-2 Human Recombinant Protein, CHO

PROTP49763-2 Regular: 25ug
EUR 317
Description: PLGF2 Human Recombinant (19-170 a.a.) produced in CHO is a disulfide-linked homodimeric, glycosylated, polypeptide chain containing 152 amino acids and having a molecular mass of 33kDa.;The PLGF-2 Human Recombinant protein is purified by proprietary chromatographic techniques.

B2M Human, Beta 2 Microglobulin Human Recombinant Protein, His Tag

PROTP61769-2 Regular: 5ug
EUR 317
Description: B2M Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 120 amino acids (1-119 a.a.) and having a molecular mass of 14 kDa. The B2M is fused to a 21 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.

AHSG Alpha-2-HS-Glycoprotein Human Recombinant Protein HEK

PROTP02765-2 Regular: 10ug
EUR 317
Description: AHSG Human Recombinant produced by transfected human cells is a single polypeptide chain containing 357 amino acids (19-367). AHSG is fused to an 8 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.

FGF-2 Fibroblast Growth Factor-Basic Human Recombinant Protein

PROTP09038-2 Regular: 50ug
EUR 317
Description: Fibroblast Growth Factor-2 Human Recombinant (FGF-2) produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 154 amino acids and having a molecular mass of 17.2kDa.;The FGF-b is purified by proprietary chromatographic techniques.

TIMP2 Tissue Inhibitor of Metalloprotease 2 Human Recombinant Protein

PROTP16035-2 Regular: 20ug
EUR 317
Description: TIMP2 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 194 amino acids and having a molecular mass of 21.8kDa. 

Nori® Human Tie-2 ELISA Kit (2 plates)

GR106458-2 2 x 96-well
EUR 832

Nori® Human TIMP-2 ELISA Kit (2 plates)

GR106460-2 2 x 96-well
EUR 832

Nori® Human Trappin-2 ELISA Kit (2 plates)

GR106467-2 2 x 96-well
EUR 832

IL-16 Interleukin-16 Human Recombinant Protein, His Tag

PROTQ14005-2 Regular: 25ug
EUR 317
Description: Interleukin-16 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain (502-631 a.a) containing 150 amino acids and having a molecular mass of 15.5kDa. The IL-16 is fused to a 20 a.a His-Tag at N-Terminus.;The IL-16 is purified by proprietary chromatographic techniques.

IL-17 Interleukin-17 Human Recombinant Protein, His Tag

PROTQ16552-2 Regular: 10ug
EUR 317
Description: Interleukin-17A Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain containing 132 amino acids fragment (24-155) having a molecular weight of 19.62kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. ;The IL-17A His is purified by proprietary chromatographic techniques.

IL-29 Interleukin-29 Human Recombinant Protein, His Tag

PROTQ8IU54-2 Regular: 20ug
EUR 317
Description: IL 29 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 206 amino acids (20-200 a.a) and having a molecular mass of 22.7kDa.IL 29 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

IL-28A Interleukin-28A Human Recombinant Protein, His Tag

PROTQ8IZJ0-2 Regular: 10ug
EUR 317
Description: IL 28A Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 198 amino acids (26-200 a.a.) and having a molecular mass of 22.1kDa. IL 28A is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

IL36G Interleukin-36 Gamma Human Recombinant Protein, His Tag

PROTQ9NZH8-2 Regular: 20ug
EUR 317
Description: IL36G Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 192 amino acids (1-169) and having a molecular mass of 21.1kDa.

IL-12-p40 Interleukin-12 p40 Human Recombinant Protein

PROTP29460-2 Regular: 10ug
EUR 317
Description: Interleukin-12 p40 His Human Recombinant produced in E.Coli is single, a non-glycosylated, polypeptide chain containing 306 amino acids fragment (23-328) with an amino-terminal hexahistidine tag. ;The IL-12 p40 His is purified by proprietary chromatographic techniques.

IL-13-Variant Interleukin-13 Variant Human Recombinant Protein

PROTP35225-2 Regular: 10ug
EUR 317
Description: Interleukin-13 Variant Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 114 amino acids, with a substitution of Q for R at position 112 compared with the wild type IL-13, having a molecular mass of 12.5 kDa. ;The IL-13 Variant is purified by proprietary chromatographic techniques.

RARRES2 Human, Retinoic Acid Receptor Responder 2 Human Recombinant Protein,Sf9

PROTQ99969-2 Regular: 5ug
EUR 317
Description: RARRES2 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 146 amino acids (21-157a.a.) and having a molecular mass of 16.9kDa. (Molecular size on SDS-PAGE will appear at approximately 18-28kDa). RARRES2 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

LCN2 Neutrophil Gelatinase Associated Lipocalin/Lipocalin-2 Human Recombinant Protein

PROTP80188-2 Regular: 10ug
EUR 317
Description: LCN2 Human Recombinant produced in E.Coli is a homodimeric non-glycosylated polypeptide chains consisting of two 178 amino acids and having a molecular mass of 41.0kDa. 

TNFR2 Tumor Necrosis Factor Receptor Type 2 Human Recombinant Protein

PROTP20333-2 Regular: 20ug
EUR 317
Description: TNFR2 Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 184 amino acids and having a molecular mass of 20kDa. The TNFR2 is purified by proprietary chromatographic techniques.

IL-17F-His Interleukin-17F Human Recombinant Protein,His Tag

PROTQ96PD4-2 Regular: 25ug
EUR 317
Description: IL 17F His Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 158 amino acids (31-163) and having a molecular mass of 17.6kDa.;IL 17F His is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Nori Equine MMP-2/TIMP-2 Complex ELISA Kit (2 plates)

GR106502-2 2 x 96-well
EUR 832

Nori® Human NADPH Oxydase 2 (NOX2) ELISA Kit-2 Plates

GR111143-2 2 x 96-well
EUR 832

2-Propyl-β-D-glucuronide, 2 mg

0904-2 2 mg
EUR 162

DCTN2 (1-403) Dynactin 2 (1-403 a.a.) Human Recombinant Protein

PROTQ13561-2 Regular: 20ug
EUR 317
Description: Dynactin 2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 426 amino acids (1-403 a.a) and having a molecular mass of 46.9kDa.;DCTN2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

SOX2 Human, SRY (sex determining region Y)-box 2 Human Recombinant Protein, TAT

PROTP48431-2 Regular: 25ug
EUR 317
Description: Sox2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 330 amino acids (317 aa residues of the full length Sox2) and having a molecular mass of 36kDa.;Sox2 is fused to a 13 amino acid TAT peptide at C-terminus (GGYGRKKRRQRRR) & purified by proprietary chromatographic techniques.

IL-1-beta Interleukin-1 beta Human Recombinant Protein, His Tag

PROTP01584-2 Regular: 20ug
EUR 317
Description: Interleukin-1 beta His-Tag Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain containing 153 amino acids fragment (117-269) and having a total molecular mass of 21.88 kDa fused with an amino-terminal hexahistidine tag. ;The IL-1b His is purified by proprietary chromatographic techniques.

IL-22 Interleukin-22 Mouse Recombinant Protein, Pegylated

PROTQ9JJY9-2 Regular: 10ug
EUR 317
Description: Pegylated Interleukin-22 Mouse Recombinant produced in E.Coli is a single, non-glycosylated homodimeric polypeptide chain containing 147 amino acids and an aditional Ala amino acid at N-terminus having a molecular mass of 36 kDa as determioned by mass spectometry. However due to enlarged hydrodymanic volume it runs on the SDS-PAGE as a 50 kDa protein and in gel-filtration on Superdex 200 as over 200 kDa protein._x000D_ The Murine IL-22 is Mono-pegylated (with 20 kDa PEG) purified by proprietary chromatographic techniques. _x000D_

IL-6 Interleukin-6 Mouse Recombinant Protein, Sf9

PROTP08505-2 Regular: 10ug
EUR 317
Description: Interleukin-6 Mouse Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 193 amino acids (25-211a.a.) and having a molecular mass of 22.5kDa (Molecular size on SDS-PAGE will appear at approximately 18-28kDa). IL6 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

Nori® Human MMP-2/TIMP-4 Complex ELISA Kit (2 plates)

GR106373-2 2 x 96-well
EUR 832

Nori® Human MMP-2/TIMP-1 Complex ELISA Kit (2 plates)

GR106374-2 2 x 96-well
EUR 832

Nori® Human MMP-3/TIMP-2 Complex ELISA Kit (2 plates)

GR106376-2 2 x 96-well
EUR 832

Nori Equine MMP-2 ELISA Kit-2 Plates

GR106478-2 2 x 96-well
EUR 832

Nori Equine TIM-2 ELISA Kit (2 plates)

GR106516-2 2 x 96-well
EUR 832

Nori Canine TIM-2 ELISA Kit (2 plates)

GR115041-2 2 x 96-well
EUR 832

a.a.), TRAIL/APO 2 Ligand (114-281 a.a.) Human Recombinant Protein, Active

PROTP50591-2 Regular: 10ug
EUR 317
Description: Soluble TNF-related apoptosis-inducing ligand Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 169 amino acids _x000D_ (114-281) and having a molecular mass of 19.6 kDa._x000D_ The sTRAIL is purified by proprietary chromatographic techniques.

2 M NaCl

GR103063-2 200 mL
EUR 59

Nori® Rabbit IL-2 ELISA Kit- 2 Plates

GR144032-2 2 x 96-well
EUR 832

Nori® Monkey IL-2 ELISA Kit- 2 Plates

GR169004-2 2 x 96-well
EUR 832

Nori® Donkey IL-2 ELISA Kit- 2 Plates

GR170004-2 2 x 96-well
EUR 832

Nori® Porcine MMP-2 ELISA Kit- 2 Plates

GR113006-2 2 x 96-well
EUR 832

Nori® Mouse IL-2 ELISA Kit- 2 Plates

GR117024-2 2 x 96-well
EUR 832

Nori® Mouse IGFBP-2 ELISA Kit- 2 Plates

GR117043-2 2 x 96-well
EUR 832

Nori® Chicken Netrin-2 ELISA Kit (2 plates)

GR106184-2 2 x 96-well
EUR 832

Nori® Chicken MMP-2 ELISA Kit- 2 Plates

GR114008-2 2 x 96-well
EUR 832

Nori® Chicken IGFBP-2 ELISA Kit-2 Plates

GR114026-2 2 x 96-well
EUR 832

VEGFR2-Fc Vascular Endothelial Growth Factor Receptor-2 Fc Chimera Human Recombinant Protein

PROTP35968-2 Regular: 10ug
EUR 317
Description: Soluble VEGFR2 Fc Human Recombinant fused with the Fc part of human IgG1 produced in baculovirus is a disulfide-linked homodimeric, glycosylated, polypeptide containing 968 amino acids and having a molecular mass of 145 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding.

ENO2 Neurone Specific Enolase 2 Human protein

PROTP09104-2 Regular: 20ug
EUR 317
Description: Human Neurone Specific Enolase produced in Human CNS having a molecular mass of 45kDa.

Human Pancreas PrimaCell 2: Pancreatic Epithelial Cells

2-96123 1 Kit Ask for price

Nori Human A1AT ELISA Kit-2 Plates

GR111022-2 2 x 96-well
EUR 832

Nori Human A1PI ELISA Kit-2 Plates

GR111023-2 2 x 96-well
EUR 832

Nori Human LDHA ELISA Kit-2 Plates

GR111024-2 2 x 96-well
EUR 832

Nori Human CRP ELISA Kit-2 Plates

GR111025-2 2 x 96-well
EUR 832

Nori Human ACE ELISA Kit-2 Plates

GR111026-2 2 x 96-well
EUR 832

Nori Human Uteroglobin ELISA Kit-2 Plates

GR111027-2 2 x 96-well
EUR 832

Nori Human eNOS ELISA Kit-2 Plates

GR111031-2 2 x 96-well
EUR 832

Nori Human PCNA ELISA Kit-2 Plates

GR111032-2 2 x 96-well
EUR 832

Nori Human DR3 ELISA Kit-2 Plates

GR111049-2 2 x 96-well
EUR 832

Nori Human HSP27 ELISA Kit-2 Plates

GR111050-2 2 x 96-well
EUR 832

Nori Human TFF1 ELISA Kit-2 Plates

GR111052-2 2 x 96-well
EUR 832

Nori Human GSAP ELISA Kit-2 Plates

GR111053-2 2 x 96-well
EUR 832

Nori Human HSP60 ELISA Kit-2 Plates

GR111055-2 2 x 96-well
EUR 832

IL-8 Interleukin-8 (1-77 a.a) Human Recombinant Protein (CXCL8), His Tag

PROTP10145-2 Regular: 50ug
EUR 317
Description: Interleukin-8 Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 77 amino acids fragment (23-99) and having a total molecular mass of 13.7kDa with an amino-terminal hexahistidine tag. ;The IL-8 His is purified by proprietary chromatographic techniques.

Nori® Guinea Pig IL-2 ELISA Kit- 2 Plates

GR171004-2 2 x 96-well
EUR 832

Nori® Porcine b-defensin 2 ELISA Kit- 2 Plates

GR113081-2 2 x 96-well
EUR 832

Nori® Canine (dog) IL-2 ELISA Kit (2 plates)

GR106163-2 2 x 96-well
EUR 832

Nori® Porcine (pig) IL-2 ELISA Kit (2 plates)

GR106188-2 2 x 96-well
EUR 832

PG LIVER 2 EA*

59423-2 2 EA
EUR 192.24

Individual Reaction Mix 2

G065-2 200 reactions
EUR 167

IL36A Mouse, Interleukin-36 Alpha Mouse Recombinant Protein, His Tag

PROTQ9JLA2-2 Regular: 20ug
EUR 317
Description: IL36A Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 183 amino acids (1-160 a.a) and having a molecular mass of 20.4kDa. IL36A is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Nori Equine MMP-2/TIMP-4 Complex ELISA Kit (2 plates)

GR106503-2 2 x 96-well
EUR 832

Nori Equine MMP-2/TIMP-1 Complex ELISA Kit (2 plates)

GR106504-2 2 x 96-well
EUR 832

Nori Equine MMP-3/TIMP-2 Complex ELISA Kit (2 plates)

GR106506-2 2 x 96-well
EUR 832

Nori® Equine NADPH Oxydase 2 (NOX2) ELISA Kit-2 Plates

GR106628-2 2 x 96-well
EUR 832

Nori® Human TLR4 ELISA Kit- 2 Plates

GR111001-2 2 x 96-well
EUR 832

Nori® Human IL18 ELISA Kit- 2 Plates

GR111002-2 2 x 96-well
EUR 832

Nori® Human VEGF ELISA Kit- 2 Plates

GR111005-2 2 x 96-well
EUR 832

Nori® Human IgA ELISA Kit- 2 Plates

GR111007-2 2 x 96-well
EUR 832

Nori® Human CD24 ELISA Kit- 2 Plates

GR111008-2 2 x 96-well
EUR 832

Nori® Human HGF ELISA Kit- 2 Plates

GR111009-2 2 x 96-well
EUR 832

Nori® Human MMP-2ELISA Kit- 2 Plates

GR111010-2 2 x 96-well
EUR 832

Nori Human SP-A ELISA Kit-2 Plates

GR111028-2 2 x 96-well
EUR 832

Nori Human SP-D ELISA Kit-2 Plates

GR111029-2 2 x 96-well
EUR 832

Nori Human KL-6 ELISA Kit-2 Plates

GR111030-2 2 x 96-well
EUR 832

Nori Human NF-kB ELISA Kit-2 Plates

GR111033-2 2 x 96-well
EUR 832

Nori Human PDGF-AA ELISA Kit-2 Plates

GR111034-2 2 x 96-well
EUR 832

Nori Human PDGF-BB ELISA Kit-2 Plates

GR111035-2 2 x 96-well
EUR 832

Nori Human FGF Acidic ELISA Kit-2 Plates

GR111036-2 2 x 96-well
EUR 832

Nori Human MMP-9 ELISA Kit-2 Plates

GR111037-2 2 x 96-well
EUR 832

Nori Human TIM-1 ELISA Kit-2 Plates

GR111038-2 2 x 96-well
EUR 832

Nori Human TIM-3 ELISA Kit-2 Plates

GR111040-2 2 x 96-well
EUR 832

Nori Human TIM-4 ELISA Kit-2 Plates

GR111041-2 2 x 96-well
EUR 832

Nori Human Cytokeratin 5 ELISA Kit-2 Plates

GR111043-2 2 x 96-well
EUR 832

Nori Human Cytokeratin 18 ELISA Kit-2 Plates

GR111044-2 2 x 96-well
EUR 832

Nori Human Cytokeratin 19 ELISA Kit-2 Plates

GR111045-2 2 x 96-well
EUR 832

Nori Human Pro-ANP ELISA Kit-2 Plates

GR111046-2 2 x 96-well
EUR 832

Nori Human Pro-BNP ELISA Kit-2 Plates

GR111047-2 2 x 96-well
EUR 832

Nori Human FGF Basic ELISA Kit-2 Plates

GR111048-2 2 x 96-well
EUR 832

Nori Human LH beta ELISA Kit-2 Plates

GR111054-2 2 x 96-well
EUR 832

Nori® Human HCG ELISA Kit- 2 Plates

GR111075-2 2 x 96-well
EUR 832

Nori® Human PIGF ELISA Kit- 2 Plates

GR111078-2 2 x 96-well
EUR 832

Nori® Human IFNa ELISA Kit- 2 Plates

GR111079-2 2 x 96-well
EUR 832

Nori® Human IFNb ELISA Kit- 2 Plates

GR111080-2 2 x 96-well
EUR 832

Nori® Human GLP1 ELISA Kit- 2 Plates

GR111081-2 2 x 96-well
EUR 832

Nori® Human BDNF ELISA Kit- 2 Plates

GR111085-2 2 x 96-well
EUR 832

Nori® Human S100A12 ELISA Kit- 2 Plates

GR111086-2 2 x 96-well
EUR 832

Nori® Human Endostatin ELISA Kit- 2 Plates

GR111088-2 2 x 96-well
EUR 832

Nori® Human UCP2 ELISA Kit- 2 Plates

GR111092-2 2 x 96-well
EUR 832

Nori® Human PDGF ELISA Kit- 2 Plates

GR111094-2 2 x 96-well
EUR 832

Nori® Human RET ELISA Kit- 2 Plates

GR111100-2 2 x 96-well
EUR 832

Nori® Human KIF5B ELISA Kit- 2 Plates

GR111101-2 2 x 96-well
EUR 832

Nori® Human S100B ELISA Kit- 2 Plates

GR111102-2 2 x 96-well
EUR 832

Nori® Human HSP90 ELISA Kit- 2 Plates

GR111103-2 2 x 96-well
EUR 832

Nori® Human CTRP9 ELISA Kit-2 Plates

GR111120-2 2 x 96-well
EUR 832

Nori® Human SFRP5 ELISA Kit-2 Plates

GR111121-2 2 x 96-well
EUR 832

Nori® Human Irisin ELISA Kit-2 Plates

GR111122-2 2 x 96-well
EUR 832

Nori® Human Betatrophin ELISA Kit-2 Plates

GR111123-2 2 x 96-well
EUR 832

Nori® Human Preptin ELISA Kit-2 Plates

GR111124-2 2 x 96-well
EUR 832

Nori® Human PTH ELISA Kit-2 Plates

GR111125-2 2 x 96-well
EUR 832

Nori® Human Melotonin ELISA Kit-2 Plates

GR111127-2 2 x 96-well
EUR 832

Nori® Human FGF21 ELISA Kit-2 Plates

GR111128-2 2 x 96-well
EUR 832

Nori® Human Visfatin ELISA Kit-2 Plates

GR111129-2 2 x 96-well
EUR 832

Nori® Human Vaspin ELISA Kit-2 Plates

GR111131-2 2 x 96-well
EUR 832

Nori® Human ACE2 ELISA Kit-2 Plates

GR111140-2 2 x 96-well
EUR 832

Nori® Human iNOS ELISA Kit-2 Plates

GR111141-2 2 x 96-well
EUR 832

Nori® Human PICP ELISA Kit-2 Plates

GR111145-2 2 x 96-well
EUR 832

Nori® Human PIIINP ELISA Kit-2 Plates

GR111146-2 2 x 96-well
EUR 832

Nori® Human TLR5 ELISA Kit (2 plates)

GR106101-2 2 x 96-well
EUR 832

Nori® Human TLR3 ELISA Kit (2 plates)

GR106104-2 2 x 96-well
EUR 832

Nori® Human TLR7 ELISA Kit (2 plates)

GR106121-2 2 x 96-well
EUR 832

Nori® Human TLR9 ELISA Kit (2 plates)

GR106122-2 2 x 96-well
EUR 832

Nori® Human BMP1 ELISA Kit (2 plates)

GR106189-2 2 x 96-well
EUR 832

Nori® Human BMP2 ELISA Kit (2 plates)

GR106190-2 2 x 96-well
EUR 832

Nori® Human BMP3 ELISA Kit (2 plates)

GR106191-2 2 x 96-well
EUR 832

Nori® Human BMP4 ELISA Kit (2 plates)

GR106192-2 2 x 96-well
EUR 832

Nori® Human BMP5 ELISA Kit (2 plates)

GR106193-2 2 x 96-well
EUR 832

Nori® Human BMP6 ELISA Kit (2 plates)

GR106194-2 2 x 96-well
EUR 832

Nori® Human BMP7 ELISA Kit (2 plates)

GR106195-2 2 x 96-well
EUR 832

Nori® Human BMP8a ELISA Kit (2 plates)

GR106196-2 2 x 96-well
EUR 832

Nori® Human AgRP ELISA Kit (2 plates)

GR106241-2 2 x 96-well
EUR 461

Nori® Human ALCAM ELISA Kit (2 plates)

GR106242-2 2 x 96-well
EUR 461

Nori® Human Angiogenin ELISA Kit (2 plates)

GR106243-2 2 x 96-well
EUR 832

Nori® Human BCAM ELISA Kit (2 plates)

GR106249-2 2 x 96-well
EUR 832

Nori® Human CD14 ELISA Kit (2 plates)

GR106257-2 2 x 96-well
EUR 832

Nori® Human CD200 ELISA Kit (2 plates)

GR106258-2 2 x 96-well
EUR 832

Nori® Human CD97 ELISA Kit (2 plates)

GR106260-2 2 x 96-well
EUR 832

Conclusion: IL-18 genes may differ in certain populations, different ethnic groups and geographic regions. IL-18 polymorphisms may not be used as a marker of metabolic syndrome.

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